Recombinant Human Peroxisomal Erans-2-Enoyl-CoA Reductase, His-tagged

• Cat.No.: PECR-2493H
• Product Overview: Recombinant human PECR protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 35.1 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-303aa
• Description: Peroxisomal trans-2-enoyl-CoA reductase, also known as PECR, the key enzyme for a proposed peroxisomal chain elongation pathway. This proein was mainly expressed in liver and kidney.
• Form: Liquid. In 20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 2mM DTT, 0.15M NaCl.
• Molecular Mass: 35.1 kDa (327aa), confirmed by MALDI-TOF.
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMASWAK GRSYLAPGLL QGQVAIVTGG ATGIGKAIVK ELLELGSNVV IASRKLERLK SAADELQANL PPTKQARVIP IQCNIRNEEE VNNLVKSTLD TFGKINFLVN NGGGQFLSPA EHISSKGWHA VLETNLTGTF YMCKAVYSSW MKEHGGSIVN IIVPTKAGFP LAVHSGAARA GVYNLTKSLA LEWACSGIRI NCVAPGVIYS QTAVENYGSW GQSFFEGSFQ KIPAKRIGVP EEVSSVVCFL LSPAASFITG QSVDVDGGRS LYTHSYEVPD HDNWPKGAGD LSVVKKMKET FKEKAKL
• Purity: >95% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml (determined by Bradford)

Gene Information

• Gene Name: PECR peroxisomal trans-2-enoyl-CoA reductase [ Homo sapiens ]
• Official Symbol: PECR
• Synonyms: PECR; peroxisomal trans-2-enoyl-CoA reductase; HSA250303; SDR29C1; short chain dehydrogenase/reductase family 29C; member 1; TERP; DCR-RP; pVI-ARL; 2,4-dienoyl-CoA reductase-related protein; putative short chain alcohol dehydrogenase; short chain dehydrogenase/reductase family 29C, member 1; DCRRP; PVIARL; HPDHASE
• Gene ID: 55825
• mRNA Refseq: NM_018441
• Protein Refseq: NP_060911
• MIM: 605843
• UniProt ID: Q9BY49
• Chromosome Location: 2q35
• Pathway: Biosynthesis of unsaturated fatty acids, organism-specific biosystem; Biosynthesis of unsaturated fatty acids, conserved biosystem; Fatty Acid Biosynthesis, organism-specific biosystem; Mitochondrial LC-Fatty Acid Beta-Oxidation, organism-specific biosystem; Peroxisome, organism-specific biosystem; Peroxisome, conserved biosystem
• Function: nucleotide binding; oxidoreductase activity; trans-2-enoyl-CoA reductase (NADPH) activity