Recombinant Human Peptidylprolyl Isomerase (cyclophilin)-Like 1

• Cat.No.: PPIL1-1753H

Specification

• ProductOverview: Recombinant PPIL1,fused to His-tag at C-terminus, was expressed in E. coli and purified byconventional chromatography techniques.
• Description: Peptidylprolylisomerase (cyclophilin)-like 1, also known as PPIL1, is a member ofpeptidyl-propyl cis-trans isomerase (PPIase) family, which catalyzes thecis-trans isomerization of proline imidic peptide bonds in oligopeptides andaccelerates the folding of proteins. Human PPIL1 might play an important rolein proliferation of cancer cells through modulation of phosphorylation ofstathmin. So it is expected as a novel molecular target for colon-cancertherapy.
• Concentration: 1 mg/ml
• Source: Human
• Host: E.coli
• Form: Supplied as a liquid in20mM Tris-HCl, pH 8.0, containing 20% glycerol.
• Purity: > 95% by SDS -PAGE
• Sequence: 1-166 amino acids:MAAIPPDSWQ PPNVYLETSM GIIVLELYWK HAPKTCKNFA ELARRGYYNG TKFHRIIKDF MIQGGDPTGTGRGGASIYGK QFEDELHPDL KFTGAGILAM ANAGPDTNGS QFFVTLAPTQ WLDGKHTIFG RVCQGIGMVNRVGMVETNSQ DRPVDDVKII KAYPSGLEHH HHHH
• MolecularMass: 19.3 kDa (174 aa),confirmed by MALDI-TOF.
• Applications: SDS-PAGE
• Storage: Store at 4 deg C forshort term storage (1/2 weeks). Aliquot and store at -20 deg C or - 70 deg Cfor long term storage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: PPIL1
• Tag: Non

Gene Information

• Gene Name: PPIL1peptidylprolyl isomerase (cyclophilin)-like 1 [ Homo sapiens ]
• Synonyms: PPIL1;peptidylprolyl isomerase (cyclophilin)-like 1; CYPL1; hCyPX; MGC678; PPIase;CGI-124; EC 5.2.1.8; OTTHUMP00000016310; Rotamase PPIL1; rotamase PPIL1;cyclophilin-related gene 1; peptidyl-prolyl cis-trans isomerase;peptidylprolyl isomerase (cyclophilin)-like 1; peptidylprolyl isomerase-like1; peptidyl-prolyl cis-trans isomerase-like 1; Peptidyl-prolyl cis-transisomerase-like 1
• Gene ID: 51645
• mRNA Refseq: NM_016059
• Protein Refseq: NP_057143
• MIM: 601301
• UniProt ID: Q9Y3C6
• Chromosome Location: 6p21.1
• Pathway: Spliceosome
• Function: isomerase activity;peptidyl-prolyl cis-trans isomerase activity