Recombinant Human PDLIM3 cell lysate

• Cat.No.: PDLIM3-1324HCL

Specification

• Species: Human
• Tag: Non
• Description: The protein encoded by this gene contains a PDZ domain and a LIM domain, indicating that it may be involved in cytoskeletal assembly. In support of this, the encoded protein has been shown to bind the spectrin-like repeats of alpha-actinin-2 and to colocalize with alpha-actinin-2 at the Z lines of skeletal muscle. This gene is found near a region of chromosome 4 that has been implicated in facioscapulohumeral muscular dystrophy, but this gene does not appear to be involved in the disease. Two transcript variants encoding different isoforms have been found for this gene.
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: PDLIM3 PDZ and LIM domain 3 [ Homo sapiens ]
• Official Symbol: PDLIM3
• Synonyms: PDLIM3; PDZ and LIM domain 3; PDZ and LIM domain protein 3; ALP; enigma homolog; alpha-actinin-2-associated LIM protein; FLJ26096; DKFZp686L0362
• Gene ID: 27295
• mRNA Refseq: NM_001114107
• Protein Refseq: NP_001107579
• MIM: 605889
• UniProt ID: Q53GG5
• Chromosome Location: 4q35
• Function: actinin binding; metal ion binding; structural constituent of muscle; zinc ion binding