Recombinant Human PCDH12 Protein, MYC/DDK-tagged

• Cat.No.: PCDH12-547H
• Product Overview: Recombinant human PCDH12 protein, fused to MYC/DDK tag at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth. [provided by RefSeq, Jul 2008]
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10 % glycerol.
• Molecular Mass: 125.8 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: protocadherin 12[ Homo sapiens ]
• Official Symbol: PCDH12
• Synonyms: VE-cadherin-2; VECAD2
• Gene ID: 51294
• mRNA Refseq: NM_016580.2
• Protein Refseq: NP_057664.1
• MIM: 605622
• UniProt ID: Q9NPG4