Recombinant Human PCDH12 protein, T7/His-tagged

• Cat.No.: PCDH12-48H
• Product Overview: Recombinant human PCDH12 cDNA (25–718aa, derived from BC042634) fused with T7-His-TEV cleavage site Tag (29aa) at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: 25-718 a.a.
• Form: 1.0 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, arginine, DTT and Glycerol.
• AA Sequence: MASMTGGQQMGRGHHHHHHGNLYFQGGEFQEVTTLTVKYQVSEEVPSGTVIGKLSQELGREERRRQAGAAFQVLQ LPQALPIQVDSEEGLLSTGRRLDREQLCRQWDPCLVSFDVLATGDLALIHVEIQVLDINDHQPRFPKGEQELEIS ESASLRTRIPLDRALDPDTGPNTLHTYTLSPSEHFALDVIVGPDETKHAELIVVKELDREIHSFFDLVLTAYDNG NPPKSGTSLVKVNVLDSNDNSPAFAESSLALEIQEDAAPGTLLIKLTATDPDQGPNGEVEFFLSKHMPPEVLDTF SIDAKTGQVILRRPLDYEKNPAYEVDVQARDLGPNPIPAHCKVLIKVLDVNDNIPSIHVTWASQPSLVSEALPKD SFIALVMADDLDSGNNGLVHCWLSQELGHFRLKRTNGNTYMLLTNATLDREQWPKYTLTLLAQDQGLQPLSAKKQ LSIQISDINDNAPVFEKSRYEVSTRENNLPSLHLITIKAHDADLGINGKVSYRIQDSPVAHLVAIDSNTGEVTAQ RSLNYEEMAGFEFQVIAEDSGQPMLASSVSVWVSLLDANDNAPEVVQPVLSDGKASLSVLVNASTGHLLVPIETP NGLGPAGTDTPPLATHSSRPFLLTTIVARDADSGANGEPLYSIRSGNEAHLFILNPHTGQLFVNVTNASSLIGSE WELEIVVEDQGSPPLQTRALLRVMFVTSVDHLRDSARKPGALSMSMLT
• Purity: >90% by SDS-PAGE
• Applications: 1. May be used for in vitro PCDH12 mediated neuronal cell / placenta differentiation regulation study with this protein as either coating matrix protein or soluble factor.2. May be used as PCDH12 protein-protein interaction assay.3. Potential diagnostic biomarker protein for pre-eclampsia.4. As antigen for specific antibody production.
• Storage: Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days.

Gene Information

• Gene Name: PCDH12 protocadherin 12 [ Homo sapiens ]
• Official Symbol: PCDH12
• Synonyms: PCDH12; protocadherin 12; protocadherin-12; VE cadherin 2; VE-cad-2; VE-cadherin 2; vascular cadherin-2; vascular endothelial cadherin 2; vascular endothelial cadherin-2; VECAD2; VE-cadherin-2
• Gene ID: 51294
• mRNA Refseq: NM_016580
• Protein Refseq: NP_057664
• MIM: 605622
• UniProt ID: Q9NPG4
• Chromosome Location: 5q31.3
• Function: calcium ion binding