PCDH12
-
Official Full Name
protocadherin 12 -
Overview
This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth. -
Synonyms
PCDH12;protocadherin 12;protocadherin-12;VE cadherin 2;VE-cad-2;VE-cadherin 2;vascular cadherin-2;vascular endothelial cadherin 2;vascular endothelial cadherin-2;VECAD2;VE-cadherin-2
Recombinant Proteins
- Human
- Mouse
- Rat
- E.coli
- Mammalian cells
- HEK293T
- HEK293
- GST
- His
- His&T7
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| PCDH12-1552H | Recombinant Human PCDH12, GST-tagged | E.coli | Human | GST | 838-1187aa | |
| Pcdh12-991M |
Active Recombinant Mouse Pcdh12 Protein, His-tagged
|
Mammalian cells | Mouse | His | Leu18-Ala716 |
|
| PCDH12-48H | Recombinant Human PCDH12 protein, T7/His-tagged | E.coli | Human | His&T7 | 25-718 a.a. |
|
| Pcdh12-1903M | Recombinant Mouse Pcdh12 Protein, His-tagged | E.coli | Mouse | His | Leu18-Asp272 |
|
| Pcdh12-1904R | Recombinant Rat Pcdh12 Protein, His-tagged | E.coli | Rat | His | Leu17-Tyr216 |
|
| Pcdh12-4702M | Recombinant Mouse Pcdh12 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
|
|
| PCDH12-547H | Recombinant Human PCDH12 Protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK |
|
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| Pcdh12-6536M | Recombinant Mouse Pcdh12 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
|
|
| Pcdh12-6536M-B | Recombinant Mouse Pcdh12 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
|
Involved Pathway
PCDH12 involved in several pathways and played different roles in them. We selected most pathways PCDH12 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with PCDH12 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
PCDH12 has several biochemical functions, for example, calcium ion binding. Some of the functions are cooperated with other proteins, some of the functions could acted by PCDH12 itself. We selected most functions PCDH12 had, and list some proteins which have the same functions with PCDH12. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| calcium ion binding | CIB3,CDH20,LRP4,PCDH2G6,PSPH,ACTN4,HPCAL4,PCDHB2,SRR,SLIT1A |
Interacting Protein
PCDH12 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with PCDH12 here. Most of them are supplied by our site. Hope this information will be useful for your research of PCDH12.
BALF4 (provisional);MYBPC2
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