Recombinant Human PARK7 Protein, His-tagged

• Cat.No.: PARK7-2549H
• Product Overview: Recombinant Human PARK7 Protein (Ala2-Asp189) with a N-His tag was expressed in E. coli.

Specification

• Description: The product of this gene belongs to the peptidase C56 family of proteins. It acts as a positive regulator of androgen receptor-dependent transcription. It may also function as a redox-sensitive chaperone, as a sensor for oxidative stress, and it apparently protects neurons against oxidative stress and cell death. Defects in this gene are the cause of autosomal recessive early-onset Parkinson disease 7. Two transcript variants encoding the same protein have been identified for this gene.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 43.4 kDa
  Accurate Molecular Mass: 24 kDa
• Protein length: Ala2-Asp189
• Endotoxin: <1.0 EU per 1µg (determined by the LAL method).
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: PARK7 parkinson protein 7 [ Homo sapiens (human) ]
• Official Symbol: PARK7
• Synonyms: PARK7; parkinson protein 7; Parkinson disease (autosomal recessive, early onset) 7; protein DJ-1; DJ 1; DJ1; oncogene DJ1; DJ-1; FLJ27376; FLJ34360; FLJ92274
• Gene ID: 11315
• mRNA Refseq: NM_001123377
• Protein Refseq: NP_001116849
• MIM: 602533
• UniProt ID: Q99497