Recombinant Human Ovarian Tumor Suppressor Candidate 2, His-tagged

• Cat.No.: OVCA2-6939H
• Product Overview: Recombinant human OVCA2 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-227aa
• Description: OVCA2 belongs to the UPF0483 family. It is ubiquitously expressed and its expression is regulated by retinoids. OVCA2 interacts with apoptosis-related protein Bag-1, indicating that this protein may participate in cell proliferation. Due to its structural and catalytic characteristics, OVCA2 is thought to act as a serine-hydrolase and, because of its reduced expression in ovarian and other tumor cell lines, it may play a role in tumor suppression.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.1M NaCl, 10% glycerol, 1mM DTT.
• Molecular Mass: 26.9 kDa (251aa), confirmed by MALDI-TOF (Molecular weight on SDS-PAGE will appear higher).
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMAAQRP LRVLCLAGFR QSERGFREKT GALRKALRGR AELVCLSGPH PVPDPPGPEG ARSDFGSCPP EEQPRGWWFS EQEADVFSAL EEPAVCRGLE ESLGMVAQAL NRLGPFDGLL GFSQGAALAA LVCALGQAGD PRFPLPRFIL LVSGFCPRGI GFKESILQRP LSLPSLHVFG DTDKVIPSQE SVQLASQFPG AITLTHSGGH FIPAAAPQRQ AYLKFLDQFA E
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: OVCA2 ovarian tumor suppressor candidate 2 [ Homo sapiens ]
• Official Symbol: OVCA2
• Synonyms: OVCA2; ovarian tumor suppressor candidate 2; ovarian cancer-associated gene 2 protein; candidate tumor suppressor in ovarian cancer 2; ovarian cancer gene-2 protein
• Gene ID: 124641
• mRNA Refseq: NM_080822
• Protein Refseq: NP_543012
• MIM: 607896
• UniProt ID: Q8WZ82
• Chromosome Location: 17p13.3
• Function: hydrolase activity