OVCA2
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Official Full Name
OVCA2 ovarian tumor suppressor candidate 2 -
Overview
Chromosome 17 is a hotspot for chromosomal aberrations in breast and ovarian cancer. Candidate oncogenes and tumor suppressors located on this chromosome include OVCA1 and OVCA2, p53, BRCA1, HER2/neu and others. OVCA1 and 2 map to a highly conserved region on human chromosome 17p13.3 that is deleted in 80% of ovarian cancers and shows frequent loss of heterozygosity in breast cancers. OVCA1 is induced by BRCA1 and is closely linked to p53, a well-known tumor suppressor gene. The close linkage of OVCA1 and p53 suggests that coordinated loss of the two genes may lead to ovarian, breast and other tumor types -
Synonyms
OVCA2;ovarian tumor suppressor candidate 2;ovarian cancer-associated gene 2 protein;candidate tumor suppressor in ovarian cancer 2;ovarian cancer gene-2 protein
Recombinant Proteins
- Human
- Mouse
- Zebrafish
- E.coli
- Mammalian Cell
- HEK293
- HEK293T
- GST
- His
- Non
- Myc&DDK
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| OVCA2-1482H | Recombinant Human OVCA2, GST-tagged | E.coli | Human | GST | 1-227aa | |
| OVCA2-12249M | Recombinant Mouse OVCA2 Protein | Mammalian Cell | Mouse | His |
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| OVCA2-2743Z | Recombinant Zebrafish OVCA2 | Mammalian Cell | Zebrafish | His |
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| OVCA2-6939H | Recombinant Human Ovarian Tumor Suppressor Candidate 2, His-tagged | E.coli | Human | His | 1-227aa |
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| OVCA2-3510HCL | Recombinant Human OVCA2 293 Cell Lysate | HEK293 | Human | Non |
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| Ovca2-4630M | Recombinant Mouse Ovca2 Protein, Myc/DDK-tagged | HEK293T | Mouse | Myc&DDK |
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| OVCA2-6442M | Recombinant Mouse OVCA2 Protein, His (Fc)-Avi-tagged | HEK293 | Mouse | His&Fc&Avi |
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| OVCA2-6442M-B | Recombinant Mouse OVCA2 Protein Pre-coupled Magnetic Beads | HEK293 | Mouse |
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| OVCA2-831H | Recombinant Human OVCA2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293T | Human | Myc&DDK |
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Involved Pathway
OVCA2 involved in several pathways and played different roles in them. We selected most pathways OVCA2 participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with OVCA2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
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Protein Function
OVCA2 has several biochemical functions, for example, hydrolase activity. Some of the functions are cooperated with other proteins, some of the functions could acted by OVCA2 itself. We selected most functions OVCA2 had, and list some proteins which have the same functions with OVCA2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| hydrolase activity | MMP30,RNASEL3,PSMC1B,OTUD7A,MCM3L,DDX39AA,Gzmd,HE1A,PL10,LIPN |
Interacting Protein
OVCA2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with OVCA2 here. Most of them are supplied by our site. Hope this information will be useful for your research of OVCA2.
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