Recombinant Human OSM Protein

Description :	This gene encodes a member of the leukemia inhibitory factor/oncostatin-M (LIF/OSM) family of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a secreted cytokine and growth regulator that inhibits the proliferation of a number of tumor cell lines. This protein also regulates the production of other cytokines, including interleukin 6, granulocyte-colony stimulating factor and granulocyte-macrophage colony stimulating factor in endothelial cells. This gene and the related gene, leukemia inhibitory factor, also present on chromosome 22, may have resulted from the duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.
Source :	E. coli
Form :	Lyophilized from a sterile solution containing 20 mM phosphate buffer, pH7.4. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Molecular Mass :	28.6 kDa
Endotoxin :	< 0.1 EU per µg protein as determined by LAL test
Purity :	>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration :	Resuspend the protein to the desired concentration in proper buffer.
Tag :	Non
Protein length :	25-221 a.a.

Gene Name	OSM oncostatin M [ Homo sapiens ]
Official Symbol	OSM
Synonyms	OSM; oncostatin M; oncostatin-M; MGC20461;
Gene ID	5008
mRNA Refseq	NM_020530
Protein Refseq	NP_065391
MIM	165095
UniProt ID	P13725