Recombinant Human NPPB protein, His & GST-tagged

• Cat.No.: NPPB-893H
• Product Overview: Recombinant Human NPPB fused with His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Description: This gene is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Mutations in this gene have been associated with postmenopausal osteoporosis.
• Purity: ≥ 85% (SDS-PAGE)
• Applications: ELISA
• Storage: Aliquot and store at -20 or -80 ℃. Avoid repeated freeze/thaw cycles
• Storage buffer: 1×PBS Buffer, Sarkosyl (0.15% m/v)

Gene Information

• Gene Name: NPPB natriuretic peptide B [ Homo sapiens (human) ]
• Official Symbol: NPPB
• Synonyms: BNP; brain type natriuretic peptide; gamma-brain natriuretic peptide; natriuretic peptide precursor B; natriuretic protein
• Gene ID: 4879
• mRNA Refseq: NM_002521.2
• Protein Refseq: NP_002512.1
• UniProt ID: P16860