Recombinant Human NOX1 protein, His-tagged

• Cat.No.: NOX1-1359H
• Product Overview: Recombinant Human NOX1(Met235~Asn488) fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Met235~Asn488
• Description: This gene encodes a member of the NADPH oxidase family of enzymes responsible for the catalytic one-electron transfer of oxygen to generate superoxide or hydrogen peroxide. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
• Form: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Molecular Mass: 31.1kDa
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: > 95%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
  If bio-activity of the protein is needed, please check active protein.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Reconstitution: Reconstitute in PBS or others.

Gene Information

• Gene Name: NOX1 NADPH oxidase 1 [ Homo sapiens ]
• Official Symbol: NOX1
• Synonyms: NOX1; NADPH oxidase 1; GP91 2; mitogenic oxidase (pyridine nucleotide dependent superoxide generating); MOX1; NADPH oxidase 1 variant NOH 1L; NADPH oxidase homolog 1; NOH 1; NOH1; MOX-1; NOX-1; mitogenic oxidase 1; NADPH oxidase homolog-1; NADPH oxidase 1 variant NOH-1L; NADH/NADPH mitogenic oxidase subunit P65-MOX; mitogenic oxidase (pyridine nucleotide-dependent superoxide-generating); NOH-1; GP91-2
• Gene ID: 27035
• mRNA Refseq: NM_007052
• Protein Refseq: NP_008983
• MIM: 300225
• UniProt ID: Q9Y5S8
• Chromosome Location: Xq22
• Pathway: Leukocyte transendothelial migration, organism-specific biosystem; Leukocyte transendothelial migration, conserved biosystem; Osteoclast differentiation, organism-specific biosystem; Osteoclast differentiation, conserved biosystem; Phagosome, organism-specific biosystem; Phagosome, conserved biosystem; RAC1 signaling pathway, organism-specific biosystem
• Function: NADP binding; Rac GTPase binding; electron carrier activity; flavin adenine dinucleotide binding; iron ion binding; metal ion binding; oxidoreductase activity; protein binding; superoxide-generating NADPH oxidase activity; superoxide-generating NADPH oxidase activity; voltage-gated ion channel activity; voltage-gated proton channel activity