Recombinant Human NEK1

Cat.No. : NEK1-29277TH
Product Overview : Recombinant fragment of Human NEK1 with an N terminal proprietary tag; Predicted MWt 36.63 kDa.
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Species : Human
Source : Wheat Germ
Tag : Non
Protein Length : 100 amino acids
Description : The protein encoded by this gene is a serine/threonine kinase involved in cell cycle regulation. The encoded protein is found in a centrosomal complex with FEZ1, a neuronal protein that plays a role in axonal development. Defects in this gene are a cause of polycystic kidney disease (PKD). Several transcript variants encoding different isoforms have been found for this gene.
Molecular Weight : 36.630kDa inclusive of tags
Tissue specificity : High fetal expression in the brain and kidney.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : DVDKSVQPEPFFHKVVHSEHLNLVPQVQSVQCSPEESFAFRSHSHLPPKNKNKNSLLIGLSTGLFDANNPKMLRTCSLPDLSKLFRTLMDVPTVGDVRQD
Sequence Similarities : Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.Contains 1 protein kinase domain.
Gene Name NEK1 NIMA (never in mitosis gene a)-related kinase 1 [ Homo sapiens ]
Official Symbol NEK1
Synonyms NEK1; NIMA (never in mitosis gene a)-related kinase 1; serine/threonine-protein kinase Nek1; KIAA1901; NY REN 55;
Gene ID 4750
mRNA Refseq NM_001199397
Protein Refseq NP_001186326
MIM 604588
Uniprot ID Q96PY6
Chromosome Location 4q32.3
Function ATP binding; metal ion binding; nucleotide binding; protein binding; protein kinase activity;

Not For Human Consumption!

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