Recombinant Human Nei Endonuclease VIII-like 2 (E. coli)
Cat.No. : | NEIL2-586H |
Product Overview : | Recombinant human NEIL2 was expressed in and purified fromE. coli. |
- Specification
- Gene Information
- Related Products
- Download
Species : | Human |
Source : | E.coli |
Tag : | Non |
Description : | NEIL2 is a DNA glycosylase involved in base excision repair of oxidative DNA damage. It is a member of the Fpg/Nei/NEIL family of bi-functional DNA glycosylases. Following its glycosylase action, NEIL2 catalyzes sequential β-elimination and δ-elimination reactions via its associated AP lyase. This results in a one-nucleotide gap in DNA containing a 3' phosphate group. A phosphatase is needed to remove the 3'phosphate group before DNA repair synthesis can occur. |
Purity : | Apparent homogeneity by SDS-PAGE and Coomassie blue staining. |
Formulation : | 20 mM Tris-HCl, pH 7.5, 300 mM NaCl, 10% glycerol. |
Storage : | Store at -70°C. Aliquot to avoid repeated freezing and thawing. |
Gene Name | NEIL2 nei endonuclease VIII-like 2 (E. coli) [ Homo sapiens ] |
Synonyms | NEIL2; nei endonuclease VIII-like 2 (E. coli); NEH2; NEI2; MGC2832; MGC4505; FLJ31644; nei like 2; EC 4.2.99.18; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Nei-like protein 2; Nei homolog 2; Nei-like 2 |
Gene ID | 252969 |
mRNA Refseq | NM_001135746 |
Protein Refseq | NP_001129218 |
MIM | 608933 |
UniProt ID | Q969S2 |
Chromosome Location | 8p23.1 |
Pathway | Base excision repair |
Function | DNA-(apurinic or apyrimidinic site) lyase activity; damaged DNA binding; hydrolase activity, hydrolyzing N-glycosyl compounds; lyase activity; metal ion binding; microtubule binding; zinc ion binding |
◆ Recombinant Proteins | ||
NEIL2-2042H | Recombinant Human Nei Endonuclease VIII-like 2 (E. coli) | +Inquiry |
NEIL2-586H | Recombinant Human Nei Endonuclease VIII-like 2 (E. coli) | +Inquiry |
Neil2-4366M | Recombinant Mouse Neil2 Protein, Myc/DDK-tagged | +Inquiry |
NEIL2-15866H | Recombinant Human NEIL2, His-tagged | +Inquiry |
NEIL2-1963H | Recombinant Human Nei Endonuclease VIII-like 2 (E. coli), His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
NEIL2-3881HCL | Recombinant Human NEIL2 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
Inquiry
- Reviews
- Q&As
Ask a Question for All NEIL2 Products
Required fields are marked with *
My Review for All NEIL2 Products
Required fields are marked with *
0
Inquiry Basket