Recombinant Human NAT2 cell lysate

• Cat.No.: NAT2-1169HCL

Specification

• Species: Human
• Tag: Non
• Description: This gene encodes an enzyme that functions to both activate and deactivate arylamine and hydrazine drugs and carcinogens. Polymorphisms in this gene are responsible for the N-acetylation polymorphism in which human populations segregate into rapid, intermediate, and slow acetylator phenotypes. Polymorphisms in this gene are also associated with higher incidences of cancer and drug toxicity. A second arylamine N-acetyltransferase gene (NAT1) is located near this gene (NAT2).
• Size: 100 ul
• Storage Buffer: 1X Sample Buffer (50 mM Tris-HCl, 2% SDS, 10% glycerol, 300 mM 2-mercaptoethanol, 0.01% Bromophenol blue)
• Applications: Western Blot

Gene Information

• Gene Name: NAT2 N-acetyltransferase 2 (arylamine N-acetyltransferase) [ Homo sapiens ]
• Official Symbol: NAT2
• Synonyms: NAT2; N-acetyltransferase 2 (arylamine N-acetyltransferase); AAC2; arylamine N-acetyltransferase 2; arylamide acetylase 2; N-acetyltransferase type 2; PNAT; NAT-2
• Gene ID: 10
• mRNA Refseq: NM_000015
• Protein Refseq: NP_000006
• MIM: 612182
• UniProt ID: P11245
• Chromosome Location: 8p22
• Pathway: Acetylation, organism-specific biosystem; Biological oxidations, organism-specific biosystem; Caffeine metabolism, organism-specific biosystem; Caffeine metabolism, conserved biosystem; Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Metabolic pathways, organism-specific biosystem
• Function: acetyltransferase activity; arylamine N-acetyltransferase activity; transferase activity, transferring acyl groups