Recombinant Human MYBPC2 protein, MYC/DDK-tagged

• Cat.No.: MYBPC2-290H
• Product Overview: Recombinant Human MYBPC2 fused with MYC/DDK tag at C-terminal was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 127.9 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: MYBPC2 myosin binding protein C, fast type [ Homo sapiens ]
• Official Symbol: MYBPC2
• Synonyms: MYBPC; MYBPCF; C-protein, skeletal muscle fast isoform; fast MyBP-C; fast-type muscle myosin-binding-protein C
• Gene ID: 4606
• mRNA Refseq: NM_004533
• Protein Refseq: NP_004524
• MIM: 160793
• UniProt ID: Q14324
• Chromosome Location: 19q13.33
• Pathway: Muscle contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem; Striated Muscle Contraction, organism-specific biosystem
• Function: actin binding; protein binding; structural constituent of muscle