Recombinant Human MYBPC2 Protein, His tagged

• Cat.No.: MYBPC2-2007H
• Product Overview: Recombinant Human MYBPC2 Protein with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively.
• Form: Lyophilized
• Molecular Mass: The protein has a calculated MW of 50 kDa.
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMASMTGGQQMGRGSEFRTEPLHLIVEDVTDTTTTLKWRPPNRIGAGGIDGYLVEYCLEGSEEWVPANTEPVERCGFTVKNLPTGARILFRVVGVNIAGRSEPATLAQPVTIREIAEPPKIRLPRHLRQTYIRKVGEQLNLVVPFQGKPRPQVVWTKGGAPLDTSRVHVRTSDFDTVFFVRQAARSDSGEYELSVQIENMKDTATIRIRVVEKAGPPINVMVKEVWGTNALVEWQAPKDDGNSEIMGYFVQKADKKTMEWFNVYERNRHTSCTVSDLIVGNEYYFRVYTENICGLSDSPGVSKNTARILKTGITFKPFEYKEHDFRMAPKFLTPLIDRVVVAGYSAALNCAVRGHPKPKVVWMKNKMEIREDPKFLITNYQGVLTLNIRRPSPFDAGTYTCRAVNELGEALAECKLEVRVPQ
• Endotoxin: < 1 EU/μg
• Purity: > 90% by SDS-PAGE
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Lyophilized from 50 mM Tris-HCl, 300 mM NaCl, pH8.0, 1% SKL, 6% trehalose
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 13.1 mg/mL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.

Gene Information

• Gene Name: MYBPC2 myosin binding protein C2 [ Homo sapiens (human) ]
• Official Symbol: MYBPC2
• Synonyms: MYBPC2; myosin binding protein C2; MYBPC; MYBPCF; fsMyBP-C; myosin-binding protein C, fast-type; fast MyBP-C; fast skeletal-type muscle myosin-binding-protein C; fast-type muscle myosin-binding-protein C; myosin binding protein C, fast type; testicular tissue protein Li 126
• Gene ID: 4606
• mRNA Refseq: NM_004533
• Protein Refseq: NP_004524
• MIM: 160793
• UniProt ID: Q14324