MYBPC2
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Official Full Name
myosin binding protein C, fast type -
Overview
This gene encodes a member of the myosin-binding protein C family. This family includes the fast-, slow- and cardiac-type isoforms, each of which is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. The protein encoded by this locus is referred to as the fast-type isoform. Mutations in the related but distinct genes encoding the slow-type and cardiac-type isoforms have been associated with distal arthrogryposis, type 1 and hypertrophic cardiomyopathy, respectively. -
Synonyms
MYBPC2;myosin binding protein C, fast type;C-protein, skeletal muscle fast isoform;fast MyBP-C;myosin-binding protein C, fast-type
Recombinant Proteins
- Human
- Chicken
- Mouse
- HEK293
- E.coli
- Mammalian Cells
- Yeast
- Myc&DDK
- His
- Flag
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| MYBPC2-290H | Recombinant Human MYBPC2 protein, MYC/DDK-tagged | HEK293 | Human | Myc&DDK | ||
| MYBPC2-2007H | Recombinant Human MYBPC2 Protein, His tagged | E.coli | Human | His | ||
| MYBPC2-3451C | Recombinant Chicken MYBPC2 | Mammalian Cells | Chicken | His |
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| MYBPC2-1602H | Recombinant Human MYBPC2 Protein, Myc/DDK-tagged, C13 and N15-labeled | HEK293 | Human | Myc&DDK |
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| MYBPC2-1652H | Recombinant Human MYBPC2 Protein (739-1141 aa), His-tagged | Yeast | Human | His | 739-1141 aa |
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| Mybpc2-4235M | Recombinant Mouse Mybpc2 Protein, Myc/DDK-tagged | HEK293 | Mouse | Myc&DDK |
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| MYBPC2-5754HFL | Recombinant Full Length Human MYBPC2 protein, Flag-tagged | Mammalian Cells | Human | Flag | Full L. |
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Involved Pathway
MYBPC2 involved in several pathways and played different roles in them. We selected most pathways MYBPC2 participated on our site, such as Muscle contraction,Striated Muscle Contraction, which may be useful for your reference. Also, other proteins which involved in the same pathway with MYBPC2 were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|---|
| Muscle contraction | DESMA,TNNI2A.3,TRIM72,TCAP,TNNI1,TNNI1B,TNNI2B.1,TNNI2A.1,TNNT3B,VIML |
| Striated Muscle Contraction | MYOM1,TNNI2B.1,TNNI1,ACTA1,MYLZ3,TNNI1B,DES,CMLC1,TCAP,MYBPC1 |
Protein Function
MYBPC2 has several biochemical functions, for example, actin binding,protein binding,structural constituent of muscle. Some of the functions are cooperated with other proteins, some of the functions could acted by MYBPC2 itself. We selected most functions MYBPC2 had, and list some proteins which have the same functions with MYBPC2. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| actin binding | TNNI3,EPB49,EPS8,MKL1,TPM3,SSH3,FHOD1,C19orf21,DIAP1,WASH1 |
| structural constituent of muscle | MYL5,SYNM,SMTN,DAG1,JPH1,ANKRD2,ACTN3,ASPH,TTN,MYOM1 |
| protein binding | SP100,PKD1L3,DYNLL2,DNMT3B,DNPEP,CCDC67,KCTD5,SIX3,EIF3D,TNFAIP8L2 |
Interacting Protein
MYBPC2 has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with MYBPC2 here. Most of them are supplied by our site. Hope this information will be useful for your research of MYBPC2.
FSD2;SDCBP;GAS7;FLNB;TULP3;DYSF;GABARAP;HSPA1A;MYH8;ITGB5;MSN;NF2;ACTN2;CCT6A;RANBP2;MYOM2;MYBPC1
Resources
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References
- Ackermann, MA; Kontrogianni-Konstantopoulo, A; et al. Myosin binding protein-C slow: a multifaceted family of proteins with a complex expression profile in fast and slow twitch skeletal muscles. FRONTIERS IN PHYSIOLOGY 4:-(2013).
- Kang, LHD; Hoh, JFY; et al. Chronic Low-Frequency Stimulation Transforms Cat Masticatory Muscle Fibers into Jaw-Slow Fibers. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY 59:849-863(2011).
