Recombinant Human MVP, MYC/DDK-tagged

• Cat.No.: MVP-1116H
• Product Overview: Recombinant Human MVP, fused with C-terminal MYC/DDK, was expressed in HEK293 cells.

Specification

• Species: Human
• Source: HEK293
• Tag: Myc&DDK
• Description: This gene encodes the major component of the vault complex. Vaults are multi-subunit ribonucleoprotein structures that may be involved in nucleo-cytoplasmic transport. The encoded protein may play a role in multiple cellular processes by regulating the MAP kinase, JAK/STAT and phosphoinositide 3-kinase/Akt signaling pathways. The encoded protein also plays a role in multidrug resistance, and expression of this gene may be a prognostic marker for several types of cancer. Alternatively spliced transcript variants have been observed for this gene.
• Molecular Mass: 99.1 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: MVP major vault protein [ Homo sapiens (human) ]
• Official Symbol: MVP
• Synonyms: MVP; major vault protein; LRP; lung resistance related protein; VAULT1; lung resistance-related protein
• Gene ID: 9961
• mRNA Refseq: NM_005115
• Protein Refseq: NP_005106
• MIM: 605088
• UniProt ID: Q14764
• Chromosome Location: 16p11.2
• Function: protein binding; protein kinase binding; protein phosphatase binding