Recombinant Human MRC2 Protein (Pro41-Lys505), His tagged

• Cat.No.: MRC2-3407H
• Product Overview: Recombinant human MRC2 (Pro41-Lys505) protein fused with His tag was expressed in E. coli.

Specification

• Description: May play a role as endocytotic lectin receptor displaying calcium-dependent lectin activity. Internalizes glycosylated ligands from the extracellular space for release in an endosomal compartment via clathrin-mediated endocytosis. May be involved in plasminogen activation system controlling the extracellular level of PLAUR/PLAU, and thus may regulate protease activity at the cell surface. May contribute to cellular uptake, remodeling and degradation of extracellular collagen matrices. May play a role during cancer progression as well as in other chronic tissue destructive diseases acting on collagen turnover. May participate in remodeling of extracellular matrix cooperating with the matrix metalloproteinases (MMPs).
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 52.88 kDa
• Protein length: Pro41-Lys505
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: MRC2 mannose receptor, C type 2 [ Homo sapiens (human) ]
• Official Symbol: MRC2
• Synonyms: MRC2; mannose receptor, C type 2; C-type mannose receptor 2; CD280; CLEC13E; ENDO180; KIAA0709; endocytic receptor 180; UPAR-associated protein; macrophage mannose receptor 2; C-type lectin domain family 13 member E; endocytic receptor (macrophage mannose receptor family); urokinase-type plasminogen activator receptor-associated protein; UPARAP; FLJ35911
• Gene ID: 9902
• mRNA Refseq: NM_006039
• Protein Refseq: NP_006030
• MIM: 612264
• UniProt ID: Q9UBG0