Recombinant Human MRC2 protein, His-tagged

• Cat.No.: MRC2-825H
• Product Overview: Recombinant Human MRC2 aa. (Pro41~Lys505) fused with N-terminal His tag was produced in E. coli cells.

Specification

• Description: This gene encodes a member of the mannose receptor family of proteins that contain a fibronectin type II domain and multiple C-type lectin-like domains. The encoded protein plays a role in extracellular matrix remodeling by mediating the internalization and lysosomal degradation of collagen ligands. Expression of this gene may play a role in the tumorigenesis and metastasis of several malignancies including breast cancer, gliomas and metastatic bone disease.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: 57kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Pro41~Lys505
• Endotoxin: <1.0EU per 1µg (determined by the LAL method)
• Purity: >92%
• Characteristic: The isoelectric point is 5.1.
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200μg/mL
• Storage buffer: 100mM NaHCO3, 500mM NaCl, pH8.3, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5%Trehalose and Proclin300.
• Reconstitution: Reconstitute in 100mM NaHCO3, 500mM NaCl (pH8.3) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: MRC2 mannose receptor C type 2 [ Homo sapiens (human) ]
• Official Symbol: MRC2
• Synonyms: CD280; UPARAP; CLEC13E; ENDO180; C-type lectin domain family 13 member E; UPAR-associated protein; endocytic receptor (macrophage mannose receptor family); endocytic receptor 180; macrophage mannose receptor 2; urokinase-type plasminogen activator receptor-associated protein; C-type mannose receptor 2
• Gene ID: 9902
• mRNA Refseq: NM_006039.4
• Protein Refseq: NP_006030.2
• UniProt ID: Q9UBG0