Recombinant Human MORF4L2, His-tagged

• Cat.No.: MORF4L2-3492H
• Product Overview: Recombinant human MORF4L2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: MORF4L2 is a member of the mortality factor (MORF) family of transcriptional regulator that is involved in cell growth, regulation and senescence. This protein localizes to the nucleus, and it has a protein kinase C phosphorylation site as well as a tyrosine phosphorylation site. It interacts with the Rb tumor suppressor through its helix-loop-helix and leucine zipper regions. It also has histone deacetylase activity and can either repress or promote the activity of the B-Myb promoter depending on the tissue.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 20% glycerol; 1mM DTT
• Molecular Weight: 34.4 kDa (308aa) confirmed by MALDI-TOF(Molecular weight on SDS-PAGE will appear higher)
• Purity: > 90% by SDS - PAGE
• Concentration: 0.5 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MSSRKQGSQP RGQQSAEEEN FKKPTRSNMQ RSKMRGASSG KKTAGPQQKN LEPALPGRWG GRSAENPPSG SVRKTRKNKQ KTPGNGDGGS TSEAPQPPRK KRARADPTVE SEEAFKNRME VKVKIPEELK PWLVEDWDLV TRQKQLFQLP AKKNVDAILE EYANCKKSQG NVDNKEYAVN EVVAGIKEYF NVMLGTQLLY KFERPQYAEI LLAHPDAPMS QVYGAPHLLR LFVRIGAMLA YTPLDEKSLA LLLGYLHDFL KYLAKNSASL FTASDYKVAS AEYHRKAL
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.

Gene Information

• Gene Name: MORF4L2 mortality factor 4 like 2 [ Homo sapiens ]
• Synonyms: MORF4L2; MRGX; MORFL2; KIAA0026; mortality factor 4-like protein 2; MSL3-2 protein; protein MSL3-2; OTTHUMP00000023750; OTTHUMP00000023751; OTTHUMP00000023752; OTTHUMP00000023753; OTTHUMP00000023754; OTTHUMP00000023756; MORF-related gene X protein; transcription factor-like protein MRGX
• Gene ID: 9643
• mRNA Refseq: NM_001142418
• Protein Refseq: NP_001135890
• MIM: 300409
• UniProt ID: Q15014
• Chromosome Location: Xq22
• Function: protein binding