Recombinant Human MACROH2A1 Protein (Ile109-Leu369), N-GST tagged

• Cat.No.: MACROH2A1-3755H
• Product Overview: Recombinant human MACROH2A1 (Ile109-Leu369) fused with the N-GST tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• ProteinLength: Ile109-Leu369
• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 54.59 kDa
• Purity: >90% as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02% NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: MACROH2A1 macroH2A.1 histone [ Homo sapiens (human) ]
• Official Symbol: MACROH2A1
• Synonyms: MACROH2A1; macroH2A.1 histone; H2A.y; H2A/y; H2AFY; mH2A1; H2AF12M; MACROH2A1.1; macroH2A1.2; core histone macro-H2A.1; H2A histone family member Y; histone H2A.y; histone macroH2A1; histone macroH2A1.1; histone macroH2A1.2; medulloblastoma antigen MU-MB-50.205
• Gene ID: 9555
• mRNA Refseq: NM_138609
• Protein Refseq: NP_613075
• MIM: 610054
• UniProt ID: O75367