Recombinant Human LTBR Protein, Fc-tagged

• Cat.No.: LTBR-8493H
• Product Overview: A soluble fusion protein consisting of 10 residual amino acids from murine CD8 alpha leader sequence (KPQAPELRGS), followed by the mature extracellular (192aa) domain of human LTbR (SQPQAVP…PLEPLPP) fused to (233aa) murine IgG2a Fc (EPRGPTI…FSRTPGK) was expressed in CHO.

Specification

• Description: This gene encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
• Source: CHO
• Species: Human
• Tag: Fc
• Molecular Mass: 48.9 kDa
• Applications: Recombinant human LTbR-muIg fusion protein binds to recombinant human LIGHT in EIA.
• Stability: Product should retain activity for at least 6 months after shipping date when stored as recommended.
• Storage: Store at 2-5 centigrade. Freeze/Thawing is not recommended.
• Concentration: 0.5 mg/mL
• Storage Buffer: 50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150 mM NaCl, 0.5 mg/mL Gentamicin Sulfate (as a preservative).

Gene Information

• Gene Name: LTBR lymphotoxin beta receptor [ Homo sapiens (human) ]
• Official Symbol: LTBR
• Synonyms: LTBR; lymphotoxin beta receptor; TNFCR; TNFR3; D12S370; TNFR-RP; TNFRSF3; TNFR2-RP; LT-BETA-R; TNF-R-III; tumor necrosis factor receptor superfamily member 3; lymphotoxin B receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor type III
• Gene ID: 4055
• mRNA Refseq: NM_002342
• Protein Refseq: NP_002333
• MIM: 600979
• UniProt ID: P36941