Active Recombinant Human LTBR, Fc Chimera
Cat.No. : | LTBR-746H |
Product Overview : | Recombinant Human LTBR (Accession # NP_002333) was produced in Chinese Hamster Ovary cell line, CHO-derived. |
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Species : | Human |
Source : | CHO |
Tag : | Fc |
Predicted N Terminal : | Ser28 |
Form : | Lyophilized from a 0.2 µm filtered solution in PBS. |
Bio-activity : | Measured by its ability to inhibit Lymphotoxin alpha 1/beta 2-induced IL-8 secretion in A375 human melanoma cells. Degli-Esposti, M. et al. (1997) J. Immunol. 158:1756.The ED50 for this effect is typically 2-10 ng/mL in the presence of 10 ng/mL of Recombinant Human Lymphotoxin alpha 1/beta 2. |
Molecular Mass : | Recombinant Human LTBR, Fc Chimera has a calculated MW of 48.5 kDa (monomer). In SDS-PAGE migrates as 60-66 kDa, reducing conditions. |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4ºC); After reconstitution under sterile conditions for 3 months (-70ºC). |
Gene Name | LTBR lymphotoxin beta receptor (TNFR superfamily, member 3) [ Homo sapiens ] |
Official Symbol | LTBR |
Synonyms | LTBR; lymphotoxin beta receptor (TNFR superfamily, member 3); D12S370; tumor necrosis factor receptor superfamily member 3; TNF R III; TNFCR; TNFR RP; TNFR2 RP; TNFRSF3; TNF-RIII; TNFR-III; lymphotoxin B receptor; lymphotoxin-beta receptor; TNFR superfamily, member 3; tumor necrosis factor C receptor; tumor necrosis factor receptor type III; tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor superfamily, member 3; CD18; TNFR-RP; TNFR2-RP; LT-BETA-R; TNF-R-III; |
Gene ID | 4055 |
mRNA Refseq | NM_002342 |
Protein Refseq | NP_002333 |
MIM | 600979 |
UniProt ID | P36941 |
Chromosome Location | 12p13 |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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