Recombinant Human LTA

• Cat.No.: LTA-31535TH
• Product Overview: Recombinant full length protein (Human)

Specification

• Description: The encoded protein, a member of the tumor necrosis factor family, is a cytokine produced by lymphocytes. The protein is highly inducible, secreted, and forms heterotrimers with lymphotoxin-beta which anchor lymphotoxin-alpha to the cell surface. This protein also mediates a large variety of inflammatory, immunostimulatory, and antiviral responses, is involved in the formation of secondary lymphoid organs during development and plays a role in apoptosis. Genetic variations in this gene are associated with susceptibility to leprosy type 4 and psoriatic arthritis.
• Source: E. coli
• Form: Lyophilised:Reconstitute with 20μl pure water.
• Storage: Store at -20°C, Stable for 6 months at -20°C
• Sequences of amino acids: Human TNF-beta is an 18.6 kDa protein containing 172 amino acid residues.:MLPGVGLTPSAAQTARQHPKMHLAHSTLKPAAHLIGDPSKQNSLLW RANTDRAFLQDGFSLSNNSLLVPTSGIYFVYSQVVFS GKAYSPKATSSPLYLAHEVQLFSSQYPFHVPLLSSQK MVYPGLQEPWLHSMYHGAAFQLTQGDQLSTHTDGIPH LVLSPSTVFFGAFAL
• Sequence Similarities: Belongs to the tumor necrosis factor family.
• Tag: Non
• Full Length: Full L.

Gene Information

• Gene Name: LTA lymphotoxin alpha (TNF superfamily, member 1) [ Homo sapiens ]
• Official Symbol: LTA
• Synonyms: LTA; lymphotoxin alpha (TNF superfamily, member 1); TNFB; lymphotoxin-alpha; LT; TNFSF1
• Gene ID: 4049
• mRNA Refseq: NM_000595
• Protein Refseq: NP_000586
• MIM: 153440
• Uniprot ID: P01374
• Chromosome Location: 6p21.3
• Pathway: Apoptosis, organism-specific biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem
• Function: cytokine activity; receptor binding; tumor necrosis factor receptor binding