Recombinant Human KDM4A, GST-tagged
Cat.No. : | KDM4A-7031H |
Product Overview : | Recombinant human KDM4A (1-886) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
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Species : | Human |
Source : | Sf9 Cells |
Tag : | GST |
Protein Length : | 1-886 aa |
Description : | KDM4A or lysine (K)-specific demethylase 4A is a member of the Jumonji domain 2 (JMJD2) family that encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. KDM4A functions in euchromatin to remove histone methylation marks that are associated with active transcription. KDM4A also act as a trimethylation-specific demethylase those converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~150 kDa |
Purity : | >90% |
Applications : | Western Blot |
Storage : | Store at –70°C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. Avoid freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name | KDM4A lysine (K)-specific demethylase 4A [ Homo sapiens ] |
Official Symbol | KDM4A |
Synonyms | KDM4A; lysine (K)-specific demethylase 4A; JMJD2, JMJD2A, jumonji domain containing 2 , jumonji domain containing 2A; lysine-specific demethylase 4A; JHDM3A; jumonji C domain containing histone demethylase 3A; KIAA0677; jumonji domain containing 2; jumonji domain containing 2A; jumonji domain-containing protein 2A; jumonji C domain-containing histone demethylase 3A; jmjC domain-containing histone demethylation protein 3A; JMJD2; JMJD2A; |
Gene ID | 9682 |
mRNA Refseq | NM_014663 |
Protein Refseq | NP_055478 |
MIM | 609764 |
UniProt ID | O75164 |
Chromosome Location | 1p34.1 |
Function | histone demethylase activity (H3-K36 specific); metal ion binding; oxidoreductase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; protein binding; zinc ion binding; |
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KDM4A-168H | Recombinant Human KDM4A, GST-tagged | +Inquiry |
KDM4A-094H | Recombinant Human KDM4A Protein, His-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
KDM4A-4996HCL | Recombinant Human KDM4A 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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