Recombinant Human K (lysine) Acetyltransferase 2B

• Cat.No.: KAT2B-1654H
• Product Overview: Recombinant KAT2B is useful in HAT inhibitor screening, kinetic studies and HAT substrate cleavages in vitro or in tissue culture. KAT2B can also be used as positive control in HAT activity assay.

Specification

• Cat. No.: KAT2B-1654H
• Description: KAT2B also known as K(lysine) acetyltransferase 2B (KAT2B), is a human gene and trancriptional coactivator associated with p53.
• Biological Activity: Activity of KAT2B was routinely tested for its ability to cleave HAT Substrate. A detailed assay procedure is available.
• Source: E. coli
• Species: Human
• Form: Lyophilized
• Appearance: Lyophilized powder
• Reconstitution: Reconstitute in MilliQ water to a concentration of 1 mg/ml. The solution can then be used in bioassay, or store at -20°C for future use.
• Purity: >95% by SDS-PAGE
• Storage: Store at -70°C, stable for at least 1 year as supplied. Aviod freeze/thaw cycles.
• Pathways: Androgen Receptor Signaling Pathway; Delta-Notch Signaling Pathway; E2F transcription factor network; FoxO family signaling; Gene Expression; Generic Transcription Pathway; HTLV-I infection; Notch signaling pathway; Notch-HLH transcription pathway; RNA Polymerase I Promoter Clearance; RNA Polymerase I; Regulation of Androgen receptor activity; Regulation of nuclear SMAD2/3 signaling; Signaling events mediated by HDAC Class I; TGF-beta Receptor Signaling Pathway; Transcription; p53 pathway
• Tag: Non

Gene Information

• Gene Name: KAT2B K(lysine) acetyltransferase 2B [ Homo sapiens ]
• Official Symbol: KAT2B
• Synonyms: KAT2B; K (lysine) acetyltransferase 2B; P; CAF; PCAF; P/CAF; CREBBP-associated factor; p300/CBP-associated factor; Histone acetyltransferase KAT2B; EC 2.3.1.48; Lysine acetyltransferase 2B; Histone acetylase PCAF; P300/CBP-associated factor; P/CAF; GCN5; GCN5L
• Gene ID: 8850
• mRNA Refseq: NM_003884
• Protein Refseq: NP_003875
• MIM: 602303
• UniProt ID: Q92831
• Chromosome Location: 3p24
• Function: acetyltransferase activity; cyclin-dependent protein kinase inhibitor activity; histone acetyltransferase activity; histone deacetylase binding; lysine N-acetyltransferase activity; protein binding; protein kinase binding; transcription coactivator activity; transcription cofactor activity; transcription factor binding; transferase activity, transferring acyl groups