Recombinant Human KAT2B protein, GST-tagged

• Cat.No.: KAT2B-124H
• Product Overview: Recombinant Human KAT2B(1 a.a. - 832 a.a.) fused with GST tag at N-terminal was expressed in Wheat Germ.

Specification

• Description: CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation, including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300, and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles, indicating that this protein plays a direct role in transcriptional regulation.
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Form: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
• Molecular Mass: 117.92 kDa
• Protein length: 1 a.a. - 832 a.a.
• AA Sequence: MSEAGGAGPGGCGAGAGAGAGPGAL PPQPAALPPAPPQGSPCAAAAGGSG ACGPATAVAAAGTAEGPGGGGSARI AVKKAQLRSAPRAKKLEKLGVYSAC KAEESCKCNGWKNPNPSPTPPRADL QQIIVSLTESCRSCSHALAAHVSHL ENVSEEEMNRLLGIVLDVEYLFTCV HKEEDADTKQVYFYLFKLLRKSILQ RGKPVVEGSLEKKPPFEKPSIEQGV NNFVQYKFSHLPAKERQTIVELAKM FLNRINYWHLEAPSQRRLRSPNDDI SGYKENYTRWLCYCNVPQFCDSLPR YETTQVFGRTLLRSVFTVMRRQLLE QARQEKDKLPLEKRTLILTHFPKFL SMLEEEVYSQNSPIWDQDFLSASSR TSQLGIQTVINPPPVAGTISYNSTS SSLEQPNAGSSSPACKASSGLEANP GEKRKMTDSHVLEEAKKPRVMGDIP MELINEVMSTITDPAAMLGPETNFL SAHSARDEAARLEERRGVIEFHVVG NSLNQKPNKKILMWLVGLQNVFSHQ LPRMPKEYITRLVFDPKHKTLALIK DGRVIGGICFRMFPSQGFTEIVFCA VTSNEQVKGYGTHLMNHLKEYHIKH DILNFLTYADEYAIGYFKKQGFSKE IKIPKTKYVGYIKDYEGATLMGCEL NPRIPYTEFSVIIKKQKEIIKKLIE RKQAQIRKVYPGLSCFKDGVRQIPI ESIPGIRETGWKPSGKEKSKEPRDP DQLYSTLKSILQQVKSHQSAWPFME PVKRTEAPGYYEVIRFPMDLKTMSE RLKNRYYVSKKLFMADLQRVFTNCK EYNPPESEYYKCANILEKFFFSKIK EAGLIDK
• Applications: Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.

Gene Information

• Gene Name: KAT2B K(lysine) acetyltransferase 2B [ Homo sapiens ]
• Official Symbol: KAT2B
• Synonyms: KAT2B; K(lysine) acetyltransferase 2B; p300/CBP associated factor , PCAF; histone acetyltransferase KAT2B; GCN5; GCN5L; P/CAF; histone acetylase PCAF; CREBBP-associated factor; p300/CBP-associated factor; lysine acetyltransferase 2B; histone acetyltransferase PCAF; P; CAF; PCAF
• Gene ID: 8850
• mRNA Refseq: NM_003884
• Protein Refseq: NP_003875
• MIM: 602303
• UniProt ID: Q92831
• Chromosome Location: 3p24
• Pathway: Androgen Receptor Signaling Pathway, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; E2F transcription factor network, organism-specific biosystem; FoxO family signaling, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; HTLV-I infection, organism-specific biosystem
• Function: acetyltransferase activity; cyclin-dependent protein kinase inhibitor activity; histone acetyltransferase activity; histone deacetylase binding; lysine N-acetyltransferase activity; lysine N-acetyltransferase activity; protein binding; protein kinase binding; transcription coactivator activity; transcription cofactor activity; transcription factor binding; transferase activity, transferring acyl groups