Recombinant Human IMPDH2 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | IMPDH2-4161H |
Product Overview : | IMPDH2 MS Standard C13 and N15-labeled recombinant protein (NP_000875) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | This gene encodes the rate-limiting enzyme in the de novo guanine nucleotide biosynthesis. It is thus involved in maintaining cellular guanine deoxy- and ribonucleotide pools needed for DNA and RNA synthesis. The encoded protein catalyzes the NAD-dependent oxidation of inosine-5'-monophosphate into xanthine-5'-monophosphate, which is then converted into guanosine-5'-monophosphate. This gene is up-regulated in some neoplasms, suggesting it may play a role in malignant transformation. |
Molecular Mass : | 55.8 kDa |
AA Sequence : | MADYLISGGTSYVPDDGLTAQQLFNCGDGLTYNDFLILPGYIDFTADQVDLTSALTKKITLKTPLVSSPMDTVTEAGMAIAMALTGGIGFIHHNCTPEFQANEVRKVKKYEQGFITDPVVLSPKDRVRDVFEAKARHGFCGIPITDTGRMGSRLVGIISSRDIDFLKEEEHDCFLEEIMTKREDLVVAPAGITLKEANEILQRSKKGKLPIVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKFVPYLIAGIQHSCQDIGAKSLTQVRAMMYSGELKFEKRTSSAQVEGGVHSLHSYEKRLFTRTRPLEQKLISEEDLAANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name | IMPDH2 inosine monophosphate dehydrogenase 2 [ Homo sapiens (human) ] |
Official Symbol | IMPDH2 |
Synonyms | IMPDH2; IMP (inosine 5-monophosphate) dehydrogenase 2; inosine-5-monophosphate dehydrogenase 2; IMPD 2; IMPDH 2; IMP oxireductase 2; inosine 5 phosphate dehydrogenase 2; IMP (inosine monophosphate) dehydrogenase 2; inosine monophosphate dehydrogenase type II; IMPD2; IMPDH-II; |
Gene ID | 3615 |
mRNA Refseq | NM_000884 |
Protein Refseq | NP_000875 |
MIM | 146691 |
UniProt ID | P12268 |
◆ Recombinant Proteins | ||
Impdh2-3532M | Recombinant Mouse Impdh2 Protein, Myc/DDK-tagged | +Inquiry |
IMPDH2-4535M | Recombinant Mouse IMPDH2 Protein, His (Fc)-Avi-tagged | +Inquiry |
IMPDH2-11510Z | Recombinant Zebrafish IMPDH2 | +Inquiry |
IMPDH2-439H | Recombinant Human IMPDH2 Protein(5-514aa), GST-tagged | +Inquiry |
IMPDH2-5866HF | Recombinant Full Length Human IMPDH2 Protein, GST-tagged | +Inquiry |
◆ Cell & Tissue Lysates | ||
IMPDH2-5210HCL | Recombinant Human IMPDH2 293 Cell Lysate | +Inquiry |
Not For Human Consumption!
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