Recombinant human HOXB13, His-tagged

• Cat.No.: HOXB13-2425H
• Product Overview: Recombinant human HOXB13 protein, fused to His-tag at N-terminus, was expressed in E.coli

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: HOXB13 is a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea
• Molecular Mass: 33.1kDa (307aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMEPGNYA TLDGAKDIEG LLGAGGGRNL VAHSPLTSHP AAPTLMPAVN YAPLDLPGSA EPPKQCHPCPGVPQGTSPAP VPYGYFGGGY YSCRVSRSSL KPCAQAATLA AYPAETPTAG EEYPSRPTEF AFYPGYPGTY QPMASYLDVS VVQTLGAPGE PRHDSLLPVD SYQSWALAGG WNSQMCCQGE QNPPGPFWKA AFADSSGQHP PDACAFRRGR KKRIPYSKGQ LRELEREYAA NKFITKDKRRKISAATSLSE RQITIWFQNR RVKEKKVLAK VKNSATP
• Purity: >85 % by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: HOXB13 homeobox B13 [ Homo sapiens ]
• Official Symbol: HOXB13
• Synonyms: HOXB13; homeobox B13; homeo box B13; homeobox protein Hox-B13; PSGD
• Gene ID: 10481
• mRNA Refseq: NM_006361
• Protein Refseq: NP_006352
• MIM: 604607
• UniProt ID: Q92826
• Chromosome Location: 17q21.32
• Pathway: Regulation of Androgen receptor activity, organism-specific biosystem
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity