Recombinant Human HLA-B protein, His/T7-tagged

• Cat.No.: HLA-B-392H
• Product Overview: Recombinant Human HLA-B(aa 26-309) fused with His/T7 tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&T7
• Protein Length: 26-309 a.a.
• Description: HLA-B belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from the endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa and its gene contains 8 exons.
• Form: Lyophilized from PBS, pH 7.4, 5% trehalose, 0.01% sarcosyl
• Molecular Mass: 36.7 kDa
• Purity: Greater than 95%
• Storage: Store at +4 centigrade for up to 1 month, or aliquot and store at -80 centigrade for up to 12 months. Avoid repeat freeze-thaw cycles.
• Reconstitution: Reconstitute in sterile PBS, pH 7.2-7.4.

Gene Information

• Gene Name: HLA-B major histocompatibility complex, class I, B [ Homo sapiens ]
• Official Symbol: HLA-B
• Synonyms: HLA-B; major histocompatibility complex, class I, B; ankylosing spondylitis , AS; lymphocyte antigen; MHC class I antigen SHCHA; MHC Class I HLA heavy chain; MHC class I antigen GN00104; leukocyte antigen class I-B; MHC HLA-B cell surface glycoprotein; MHC HLA-B transmembrane glycoprotein; MHC class I antigen HLA-B heavy chain; HLA class I histocompatibility antigen, B alpha chain; AS; HLAB; SPDA1; MGC111087
• Gene ID: 3106
• mRNA Refseq: NM_005514
• Protein Refseq: NP_005505
• UniProt ID: P01889
• Chromosome Location: 6p21.3
• Pathway: Adaptive Immune System, organism-specific biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Antigen Presentation: Folding, assembly and peptide loading of class I MHC, organism-specific biosystem; Antigen processing and presentation, organism-specific biosystem; Antigen processing and presentation, conserved biosystem; Antigen processing-Cross presentation, organism-specific biosystem
• Function: MHC class I receptor activity; receptor binding