Recombinant Human HIST2H3A Protein, HIS-tagged

• Cat.No.: HIST2H3A-119H
• Product Overview: Recombinant Human HIST2H3A fused with His tag at N-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is found in a histone cluster on chromosome 1. This gene is one of four histone genes in the cluster that are duplicated; this record represents the centromeric copy.
• Form: 25mM Tris, pH8.0, 150 mM NaCl, 10% glycerol, 1 % Sarkosyl. Store at -80 centigrade. Avoid repeated freeze-thaw cycles. Stable for at least 3 months from receipt of products under proper storage and handling conditions.
• Molecular Mass: 15.2 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: HIST2H3A histone cluster 2, H3a [ Homo sapiens ]
• Official Symbol: HIST2H3A
• Synonyms: HIST2H3A; histone cluster 2, H3a; histone 2, H3a; histone H3.2; H3/n; H3/o; histone H3/m; histone H3/o; HIST2H3C; HIST2H3D
• Gene ID: 333932
• mRNA Refseq: NM_001005464
• Protein Refseq: NP_001005464
• UniProt ID: Q71DI3