Recombinant Human Hepatic Leukemia Factor, His-tagged

• Cat.No.: HLF-5023H
• Product Overview: Recombinant humanHLF protein, fused to His-tag at N-terminus, was expressed in E. coli andpurified by using conventional chromatography.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: HLF, also known ashepatic leukemia factor, belongs to the bZIP family and the PAR (proline andacidic-rich) subfamily of transcription regulatory proteins. HLF binds DNAspecifically as a homodimer or heterodimer with other PAR factors. It is highlyexpressed in liver, with lower levels in lung and kidney and functions as apotent trans-activator.
• Concentration: 0.25 mg/ml
• Form: Supplied as a liquidin 20 mM Tris-HCl buffer, pH 8.0, with 40% glycerol, 0.2 M NaCl and 0.1 mMPMSF.
• Purity: > 85% by SDS-PAGE
• Sequence: 1-295 amino acids:MGSSHHHHHH SSGLVPRGSH MEKMSRPLPL NPTFIPPPYG VLRSLLENPL KLPLHHEDAF SKDKDKEKKLDDESNSPTVP QSAFLGPTLW DKTLPYDGDT FQLEYMDLEE FLSENGIPPS PSQHDHSPHP PGLQPASSAAPSVMDLSSRA SAPLHPGIPS PNCMQSPIRP GQLLPANRNT PSPIDPDTIQ VPVGYEPDPA DLALSSIPGQEMFDP
• Molecular Mass: 35.3 kDa
• Applications: SDS-PAGE
• Storage: Store at 4 deg C forshort term storage. Aliquot and store at -20 deg C or -70 deg C for long termstorage. Avoid repeated freeze/thaw cycles.
• OfficialSymbol: HLF
• Function: DNA binding;double-stranded DNA binding; protein dimerization activity; sequence-specificDNA binding; sequence-specific DNA binding transcription factor activity

Gene Information

• Gene Name: HLF hepatic leukemia factor [ Homosapiens ]
• Synonyms: HLF; hepaticleukemia factor; MGC33822; Hepatic leukemia factor
• Gene ID: 3131
• mRNA Refseq: NM_002126
• Protein Refseq: NP_002117
• MIM: 142385
• UniProt ID: Q6FHS9
• Chromosome Location: 17q22