HLF
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Official Full Name
hepatic leukemia factor -
Overview
This gene encodes a member of the proline and acidic-rich (PAR) protein family, a subset of the bZIP transcription;factors. The encoded protein forms homodimers or heterodimers with other PAR family members and binds;sequence-specific promoter elements to activate transcription. Chromosomal translocations fusing portions of this gene;with the E2A gene cause a subset of childhood B-lineage acute lymphoid leukemias. Alternatively spliced transcript;variants have been described, but their biological validity has not been determined. -
Synonyms
HLF;hepatic leukemia factor;MGC33822
Recombinant Proteins
- Human
- Rhesus macaque
- E.coli
- Mammalian Cell
- Wheat Germ
- Human
- HEK293
- In Vitro Cell Free System
- His&T7
- His
- GST
- Non
- His&Fc&Avi
| Cat.# | Product name | Source (Host) | Species | Tag | Protein Length | Price |
|---|---|---|---|---|---|---|
| HLF-209H | Recombinant Human HLF protein, T7/His-tagged | E.coli | Human | His&T7 |
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| HLF-2103R | Recombinant Rhesus monkey HLF Protein, His-tagged | Mammalian Cell | Rhesus macaque | His |
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| HLF-27715TH | Recombinant Human HLF, His-tagged | E.coli | Human | His | 295 amino acids |
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| HLF-3618H | Recombinant Human HLF, His-tagged | E.coli | Human | His |
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| HLF-4852H | Recombinant Human HLF Protein, GST-tagged | Wheat Germ | Human | GST |
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| HLF-5023H | Recombinant Human Hepatic Leukemia Factor, His-tagged | Human | Human | His |
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| HLF-5490HCL | Recombinant Human HLF 293 Cell Lysate | HEK293 | Human | Non |
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| HLF-1924R | Recombinant Rhesus Macaque HLF Protein, His (Fc)-Avi-tagged | HEK293 | Rhesus macaque | His&Fc&Avi |
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| HLF-1924R-B | Recombinant Rhesus Macaque HLF Protein Pre-coupled Magnetic Beads | HEK293 | Rhesus macaque |
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| HLF-3633HF | Recombinant Full Length Human HLF Protein, GST-tagged | In Vitro Cell Free System | Human | GST | Full L. 295 amino acids |
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Involved Pathway
HLF involved in several pathways and played different roles in them. We selected most pathways HLF participated on our site, such as , which may be useful for your reference. Also, other proteins which involved in the same pathway with HLF were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.
| Pathway Name | Pathway Related Protein |
|---|
Protein Function
HLF has several biochemical functions, for example, DNA binding,double-stranded DNA binding,sequence-specific DNA binding. Some of the functions are cooperated with other proteins, some of the functions could acted by HLF itself. We selected most functions HLF had, and list some proteins which have the same functions with HLF. You can find most of the proteins on our site.
| Function | Related Protein |
|---|---|
| DNA binding | CHTF18,ZFP82,HOXB3A,ZNF738,CCDC71L,HP1BP3,ZFP639,MYNN,TSNAX,HIST1H2BC |
| double-stranded DNA binding | DDX11,KIN,RAD51B,RAD51,SMAD2,SP8B,MTERFD2,HMGB2,TDG,TP53 |
| transcription factor activity, sequence-specific DNA binding | ZNF789,HSF5,UBN1,IKZF5,POU3F4,GTF3A,MAFA,ARNTL2,ZNF174,FOXO1A |
| sequence-specific DNA binding | GBX1,POU2F1B,ENG2A,NR1D2A,ISL1L,BARHL1A,MNX1,HOXC13A,NR0B1,HOXC10 |
Interacting Protein
HLF has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with HLF here. Most of them are supplied by our site. Hope this information will be useful for your research of HLF.
DDIT3;BATF;BATF3;DBP;yfeE;q5nf29_fratt;sbcB;pheS;recJ;gatA;sSL2;mglA10;q81kb5_bacan;moeA1;yndJ;q81un5_bacan;q81up8_bacan;rbsC
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References
- Reeves, SR; Kolstad, T; et al. Fibroblast-myofibroblast transition is differentially regulated by bronchial epithelial cells from asthmatic children. RESPIRATORY RESEARCH 16:-(2015).
- Shiga, Y; Oshima, Y; et al. Recombinant human lactoferrin-Fc fusion with an improved plasma half-life. EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES 67:136-143(2015).
