Recombinant Human HDAC2 protein, His-tagged
Cat.No. : | HDAC2-13708H |
Product Overview : | Recombinant Human HDAC2(NP_001518.3)(Met1~Pro488), fused with N-terminal His Tag, was expressed in E. coli. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | Met1~Pro488 |
Description : | This gene product belongs to the histone deacetylase family. Histone deacetylases act via the formation of large multiprotein complexes, and are responsible for the deacetylation of lysine residues at the N-terminal regions of core histones (H2A, H2B, H3 and H4). This protein forms transcriptional repressor complexes by associating with many different proteins, including YY1, a mammalian zinc-finger transcription factor. Thus, it plays an important role in transcriptional regulation, cell cycle progression and developmental events. Alternative splicing results in multiple transcript variants. |
Form : | 20mM Tris, 150mM NaCl, pH8.0, containing 0.01% SKL, 5% Trehalose. |
Molecular Mass : | 60kDa as determined by SDS-PAGE reducing conditions. |
AA Sequence : | MAYSQGGGKKKVCYYYDGDIGNYYYGQGHPMKPHRIRMTHNLLLNYGLYRKMEIYRPHKATAEEMTKYHSDEYIKFLRSIRPDNMSEYSKQMQRFNVGEDCPVFDGLFEFCQLSTGGSVAGAVKLNRQQTDMAVNWAGGLHHAKKSEASGFCYVNDIVLAILELLKYHQRVLYIDIDIHHGDGVEEAFYTTDRVMTVSFHKYGEYFPGTGDLRDIGAGKGKYYAVNFPMRDGIDDESYGQIFKPIISKVMEMYQPSAVVLQCGADSLSGDRLGCFNLTVKGHAKCVEVVKTFNLPLLMLGGGGYTIRNVARCWTYETAVALDCEIPNELPYNDYFEYFGPDFKLHISPSNMTNQNTPEYMEKIKQRLFENLRMLPHAPGVQMQAIPEDAVHEDSGDEDGEDPDKRISIRASDKRIACDEEFSDSEDEGEGGRRNVADHKKGAKKARIEEDKKETEDKKTDVKEEDKSKDNSGEKTDTKGTKSEQLSNP |
Endotoxin : | < 1.0EU per 1µg (determined by the LAL method) |
Purity : | > 90% |
Applications : | Positive Control; Immunogen; SDS-PAGE; WB. If bio-activity of the protein is needed, please check active protein. |
Notes : | The kit is designed for research use only, we will not be responsible for any issue if the kit was used in clinical diagnostic or any other procedures. |
Stability : | The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : | Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Concentration : | 200µg/mL |
Reconstitution : | Reconstitute in ddH2O to a concentration of 0.1-1.0 mg/mL. Do not vortex. |
Gene Name | HDAC2 histone deacetylase 2 [ Homo sapiens (human) ] |
Official Symbol | HDAC2 |
Synonyms | HD2; RPD3; YAF1; KDAC2 |
Gene ID | 3066 |
mRNA Refseq | NM_001527.4 |
Protein Refseq | NP_001518.3 |
MIM | 605164 |
UniProt ID | Q92769 |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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