Recombinant Human GUCA1A Protein, MYC/DDK-tagged

• Cat.No.: GUCA1A-2549H
• Product Overview: Recombinant Human GUCA1A protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes an enzyme that plays a role in the recovery of retinal photoreceptors from photobleaching. This enzyme promotes the activity of retinal guanylyl cyclase-1 (GC1) at low calcium concentrations and inhibits GC1 at high calcium concentrations. Mutations in this gene can cause cone dystrophy 3 and code-rod dystrophy 14. Alternative splicing results in multiple transcript variants.
• Form: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
• Molecular Mass: 22.7 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: GUCA1A guanylate cyclase activator 1A (retina) [ Homo sapiens ]
• Official Symbol: GUCA1A
• Synonyms: C6orf131; COD3; CORD14; GCAP; GCAP1; GUCA; GUCA1
• Gene ID: 2978
• mRNA Refseq: NM_000409
• Protein Refseq: NP_000400
• MIM: 600364
• UniProt ID: P43080