Recombinant Human GRK2 Protein, MYC/DDK-tagged
Cat.No. : | GRK2-2363H |
Product Overview : | Recombinant human GRK2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293 |
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Species : | Human |
Source : | HEK293 |
Tag : | DDK&Myc |
Description : | The product of this gene phosphorylates the beta-2-adrenergic receptor and appears to mediate agonist-specific desensitization observed at high agonist concentrations. This protein is an ubiquitous cytosolic enzyme that specifically phosphorylates the activated form of the beta-adrenergic and related G-protein-coupled receptors. Abnormal coupling of beta-adrenergic receptor to G protein is involved in the pathogenesis of the failing heart. [provided by RefSeq, Jul 2008]. |
Form : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Molecular Mass : | 79.4 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Gene Name | GRK2 G protein-coupled receptor kinase 2 [ Homo sapiens ] |
Official Symbol | GRK2 |
Synonyms | ADRBK1; BARK1; BETA-ARK1 |
Gene ID | 156 |
mRNA Refseq | NM_001619.3 |
Protein Refseq | NP_001610 |
MIM | 109635 |
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Not For Human Consumption!
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