Recombinant Human GRK2 Protein (2-221 aa), His-tagged
Cat.No. : | GRK2-1177H |
Product Overview : | Recombinant Human GRK2 Protein (2-221 aa) is produced by E. coli expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Neuroscience. Protein Description: Partial. |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 2-221 aa |
Description : | Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of th. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 29.6 kDa |
AA Sequence : | ADLEAVLADVSYLMAMEKSKATPAARASKKILLPEPSIRSVMQKYLEDRGEVTFEKIFSQKLGYLLFRDFCLNHLEEARPLVEFYEEIKKYEKLETEEERVARSREIFDSYIMKELLACSHPFSKSATEHVQGHLGKKQVPPDLFQPYIEEICQNLRGDVFQKFIESDKFTRFCQWKNVELNIHLTMNDFSVHRIIGRGGFGEVYGCRKADTGKMYAMKC |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. Please refer to it for detailed information. |
Gene Name | GRK2 G protein-coupled receptor kinase 2 [ Homo sapiens (human) ] |
Official Symbol | GRK2 |
Synonyms | BARK1; ADRBK1; BETA-ARK1; |
Gene ID | 156 |
mRNA Refseq | NM_001619 |
Protein Refseq | NP_001610 |
UniProt ID | P25098 |
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Not For Human Consumption!
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