Recombinant Human GRIA3 Protein (151-250 aa), His-tagged

• Cat.No.: GRIA3-1405H
• Product Overview: Recombinant Human GRIA3 Protein (151-250 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Neuroscience. Protein Description: Partial.

Specification

• Species: Human
• Source: Yeast
• Tag: His
• Protein Length: 151-250 aa
• Description: Receptor for glutamate that functions as ligand-gated ion channel in the central nervous syst and plays an important role in excitatory synaptic transmission. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous syst. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate.
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 14.0 kDa
• AA Sequence: SLLGHYKWEKFVYLYDTERGFSILQAIMEAAVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHSRGYHYMLANL
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: GRIA3 glutamate receptor, ionotropic, AMPA 3 [ Homo sapiens ]
• Official Symbol: GRIA3
• Synonyms: GRIA3; GluA3; GLURC; MRX94; gluR-3; dJ1171F9.1; GLUR3; GLUR-C; GLUR-K3
• Gene ID: 2892
• mRNA Refseq: NM_000828
• Protein Refseq: NP_000819
• MIM: 305915
• UniProt ID: P42263