Recombinant Human GPX2, His-tagged
Cat.No. : | GPX2-29071TH |
Product Overview : | Recombinant full length protein, corresponding to amino acids 1-190 of Human Glutathione Peroxidase 2, with an N-terminal His tag. 210 amino acids with a predicted MWt of 22 kDa |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 190 amino acids |
Description : | This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract. |
Conjugation : | HIS |
Molecular Weight : | 24.100kDa inclusive of tags |
Tissue specificity : | Mostly in liver and gastrointestinal tract, not found in heart or kidney. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | pH: 7.50Constituents:0.32% Tris HCl, 0.88% Sodium chloride, 0.02% DTT, 40% Glycerol |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHH SSGLVPRGSH MAFIAKSFYD LSAISLDGEK VDFNTFRGRA VLIENVASLC GTTTRDFTQL NELQCRFPRR LVVLGFPCNQ FGHQENCQNE EILNSLKYVR PGGGYQPTFT LVQKCEVNGQ NEHPVFAYLK DKLPYPYDDP FSLMTDPKLI IWSPVRRSDV AWNFEKFLIG PEGEPFRRYS RTFPTINIEP DIKRLLKVAI |
Sequence Similarities : | Belongs to the glutathione peroxidase family. |
Gene Name | GPX2 glutathione peroxidase 2 (gastrointestinal) [ Homo sapiens ] |
Official Symbol | GPX2 |
Synonyms | GPX2; glutathione peroxidase 2 (gastrointestinal); glutathione peroxidase 2; GSHPX GI; |
Gene ID | 2877 |
mRNA Refseq | NM_002083 |
Protein Refseq | NP_002074 |
MIM | 138319 |
Uniprot ID | P18283 |
Chromosome Location | 14q24.1 |
Pathway | Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Folate Metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; |
Function | electron carrier activity; glutathione peroxidase activity; oxidoreductase activity; |
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◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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