Recombinant Human GPX2, His-tagged

Cat.No. : GPX2-29071TH
Product Overview : Recombinant full length protein, corresponding to amino acids 1-190 of Human Glutathione Peroxidase 2, with an N-terminal His tag. 210 amino acids with a predicted MWt of 22 kDa
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Species : Human
Source : E.coli
Tag : His
Protein Length : 190 amino acids
Description : This gene is a member of the glutathione peroxidase family and encodes a selenium-dependent glutathione peroxidase that is one of two isoenzymes responsible for the majority of the glutathione-dependent hydrogen peroxide-reducing activity in the epithelium of the gastrointestinal tract. Studies in knockout mice indicate that mRNA expression levels respond to luminal microflora, suggesting a role of the ileal glutathione peroxidases in preventing inflammation in the GI tract.
Conjugation : HIS
Molecular Weight : 24.100kDa inclusive of tags
Tissue specificity : Mostly in liver and gastrointestinal tract, not found in heart or kidney.
Form : Liquid
Purity : >95% by SDS-PAGE
Storage buffer : pH: 7.50Constituents:0.32% Tris HCl, 0.88% Sodium chloride, 0.02% DTT, 40% Glycerol
Storage : Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Sequences of amino acids : MGSSHHHHHH SSGLVPRGSH MAFIAKSFYD LSAISLDGEK VDFNTFRGRA VLIENVASLC GTTTRDFTQL NELQCRFPRR LVVLGFPCNQ FGHQENCQNE EILNSLKYVR PGGGYQPTFT LVQKCEVNGQ NEHPVFAYLK DKLPYPYDDP FSLMTDPKLI IWSPVRRSDV AWNFEKFLIG PEGEPFRRYS RTFPTINIEP DIKRLLKVAI
Sequence Similarities : Belongs to the glutathione peroxidase family.
Gene Name GPX2 glutathione peroxidase 2 (gastrointestinal) [ Homo sapiens ]
Official Symbol GPX2
Synonyms GPX2; glutathione peroxidase 2 (gastrointestinal); glutathione peroxidase 2; GSHPX GI;
Gene ID 2877
mRNA Refseq NM_002083
Protein Refseq NP_002074
MIM 138319
Uniprot ID P18283
Chromosome Location 14q24.1
Pathway Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Folate Metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem; Glutathione metabolism, organism-specific biosystem;
Function electron carrier activity; glutathione peroxidase activity; oxidoreductase activity;

Not For Human Consumption!

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