Recombinant Human GNB2L1, His-tagged

• Cat.No.: GNB2L1-30327TH
• Product Overview: Recombinant full length Human RACK1 protein with an N terminal His tag. Observed MWt: 37kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: Seems to bind protein kinase C acting as an intracellular receptor to anchor the activated PKC to the cytoskeleton. May be involved in up-regulation of the activity of kinases such as PKC via binding to KRT1.
• Conjugation: HIS
• Form: Lyophilised:Reconstitute with 87 μl aqua dest.
• Storage buffer: Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5
• Storage: Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
• Sequences of amino acids: MTEQMTLRGTLKGHNGWVTQIATTPQFPDMILSASRDKTI IMWKLTRDETNYGIPQRALRGHSHFVSDVVISSDGQFA LSGSWDGTLRLWDLTTGTTTRRFVGHTKDVLSVAFSSDNRQIVSGSRDKTIKLWNTLGVCKYTVQDESHSEWVSCVRF SPNSSNPIIVSCGWDKLVKVWNLANCKLKTNHIGHTGY LNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHLYTLDGGD IINALCFSPNRYWLCAATGPSIKIWDLEGKIIVDELKQ EVISTSSKAEPPQCTSLAWSADGQTLFAGYTDNLVRVW QVTIGTR
• Sequence Similarities: Belongs to the WD repeat G protein beta family.Contains 7 WD repeats.
• Full Length: Full L.

Gene Information

• Gene Name: GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 [ Homo sapiens ]
• Official Symbol: GNB2L1
• Synonyms: GNB2L1; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; guanine nucleotide-binding protein subunit beta-2-like 1; Gnb2 rs1; H12.3; RACK1; Receptor for Activated C Kinase 1
• Gene ID: 10399
• mRNA Refseq: NM_006098
• Protein Refseq: NP_006089
• MIM: 176981
• Uniprot ID: P63244
• Chromosome Location: 5q35.3
• Pathway: CXCR4-mediated signaling events, organism-specific biosystem; Hypoxic and oxygen homeostasis regulation of HIF-1-alpha, organism-specific biosystem; IGF1 pathway, organism-specific biosystem; IL-2 Signaling Pathway, organism-specific biosystem; IL-3 Signaling Pathway, organism-specific biosystem
• Function: SH2 domain binding; ion channel inhibitor activity; protein binding; protein kinase C binding; protein phosphatase binding