Recombinant Human GDPD5, GST-tagged

• Cat.No.: GDPD5-13219H
• Product Overview: Recombinant Human GDPD5 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 1-127a.a.
• Description: This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA2 and NOLA3 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. These four H/ACA snoRNP proteins are also components of the telomerase complex. The encoded protein of this gene contains two glycine- and arginine-rich domains and is related to Saccharomyces cerevisiae Gar1p. Two splice variants have been found for this gene.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GDPD5 glycerophosphodiester phosphodiesterase domain containing 5 [ Homo sapiens ]
• Official Symbol: GDPD5
• Synonyms: GDPD5; glycerophosphodiester phosphodiesterase domain containing 5; glycerophosphodiester phosphodiesterase domain-containing protein 5; GDE2; PP1665; glycerophosphodiester phosphodiesterase 2
• Gene ID: 81544
• mRNA Refseq: NM_030792
• Protein Refseq: NP_110419
• MIM: 609632
• UniProt ID: Q8WTR4
• Chromosome Location: 11q13.4-q13.5
• Function: glycerophosphodiester phosphodiesterase activity; hydrolase activity