Recombinant Human GDF9 Protein (Gly320-Arg454), His tagged

Cat.No. : GDF9-3341H
Product Overview : Recombinant human GDF9 (Gly320-Arg454) protein fused with His tag was expressed in E. coli.
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Species : Human
Source : E.coli
Tag : His
Protein Length : Gly320-Arg454
Description : Required for ovarian folliculogenesis. Promotes primordial follicle development. Stimulates granulosa cell proliferation. Promotes cell transition from G0/G1 to S and G2/M phases, through an increase of CCND1 and CCNE1 expression, and RB1 phosphorylation. It regulates STAR expression and cAMP-dependent progesterone release in granulosa and thecal cells. Attenuates the suppressive effects of activin A on STAR expression and progesterone production by increasing the expression of inhibin B. It suppresses FST and FSTL3 production in granulosa-lutein cells.
Molecular Mass : 16.99 kDa
Purity : >90 % as determined by SDS-PAGE.
Notes : For research use only.
Storage : Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
Storage Buffer : Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
Reconstitution : Reconstitute in sterile water for a stock solution.
Shipping : In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Gene Name GDF9 growth differentiation factor 9 [ Homo sapiens (human) ]
Official Symbol GDF9
Synonyms GDF9; growth differentiation factor 9; growth/differentiation factor 9; GDF-9;
Gene ID 2661
mRNA Refseq NM_005260
Protein Refseq NP_005251
MIM 601918
UniProt ID O60383

Not For Human Consumption!

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