Recombinant Human GAB3 protein, His & T7-tagged

• Cat.No.: GAB3-1465H
• Product Overview: Recombinant Human GAB3 aa. (Lys332~Gln583 (Accession # Q8WWW8)) fused with N-terminal His & T7 tag was produced in E. coli cells.

Specification

• Description: This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His&T7
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 32.2kDa
• Protein length: Lys332~Gln583
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 7.8

Gene Information

• Gene Name: GAB3 GRB2 associated binding protein 3 [ Homo sapiens (human) ]
• Official Symbol: GAB3
• Synonyms: GAB3; GRB2 associated binding protein 3; GRB2-associated-binding protein 3; DOS/Gab family member 3; GRB2-associated binder 3; Gab3 scaffolding protein; growth factor receptor bound protein 2-associated protein 3
• Gene ID: 139716
• mRNA Refseq: NM_001081573.2
• Protein Refseq: NP_001075042.1
• UniProt ID: Q8WWW8