Recombinant Human GAB3 Protein (Lys332-Gln583), N-His tagged

• Cat.No.: GAB3-3658H
• Product Overview: Recombinant human GAB3 (Lys332-Gln583) protein fused with the N-His tag was expressed in E. coli.

Specification

• Description: This gene is a member of the GRB2-associated binding protein gene family. These proteins are scaffolding/docking proteins that are involved in several growth factor and cytokine signaling pathways, and they contain a pleckstrin homology domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. The protein encoded by this gene facilitates macrophage differentiation. Alternative splicing results in multiple transcript variants.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 30.68 kDa
• Protein length: Lys332-Gln583
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: 0.01M PBS, pH 7.4, 0.02 % NLS
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: GAB3 GRB2 associated binding protein 3 [ Homo sapiens (human) ]
• Official Symbol: GAB3
• Synonyms: GAB3; GRB2 associated binding protein 3; GRB2-associated-binding protein 3; DOS/Gab family member 3; GRB2-associated binder 3; Gab3 scaffolding protein; growth factor receptor bound protein 2-associated protein 3
• Gene ID: 139716
• mRNA Refseq: NM_080612
• Protein Refseq: NP_542179
• MIM: 300482
• UniProt ID: Q8WWW8