Recombinant Human FZD10, GST-tagged

• Cat.No.: FZD10-13064H
• Product Overview: Recombinant Human FZD10 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene is a member of the frizzled gene family. Members of this family encode 7-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. Using array analysis, expression of this intronless gene is significantly up-regulated in two cases of primary colon cancer.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 23-229a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FZD10 frizzled family receptor 10 [ Homo sapiens ]
• Official Symbol: FZD10
• Synonyms: FZD10; frizzled family receptor 10; frizzled (Drosophila) homolog 10 , frizzled 10, seven transmembrane spanning receptor , frizzled homolog 10 (Drosophila); frizzled-10; CD350; frizzled homolog 10; frizzled 10, seven transmembrane spanning receptor; Fz10; FzE7; FZ-10; hFz10
• Gene ID: 11211
• mRNA Refseq: NM_007197
• Protein Refseq: NP_009128
• MIM: 606147
• UniProt ID: Q9ULW2
• Chromosome Location: 12q24.33
• Pathway: Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; Melanogenesis, organism-specific biosystem
• Function: G-protein coupled receptor activity; PDZ domain binding; Wnt-activated receptor activity; Wnt-protein binding; protein binding; receptor activity; signal transducer activity