Recombinant Human FXN, His-tagged
Cat.No. : | FXN-13051H |
Product Overview : | Recombinant Human FXN protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
Availability | April 21, 2025 |
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Species : | Human |
Source : | E.coli |
Tag : | His |
Protein Length : | 1-210a.a. |
Description : | This nuclear gene encodes a mitochondrial protein which belongs to FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name | FXN frataxin [ Homo sapiens ] |
Official Symbol | FXN |
Synonyms | FXN; frataxin; FRDA, Friedreich ataxia; frataxin, mitochondrial; CyaY; FA; FARR; X25; Friedreich ataxia protein; FRDA; MGC57199; |
Gene ID | 2395 |
mRNA Refseq | NM_000144 |
Protein Refseq | NP_000135 |
MIM | 606829 |
UniProt ID | Q16595 |
Chromosome Location | 9q21.11 |
Pathway | HIF-2-alpha transcription factor network, organism-specific biosystem; Metabolism of proteins, organism-specific biosystem; Mitochondrial Protein Import, organism-specific biosystem; |
Function | 2 iron, 2 sulfur cluster binding; enzyme binding; ferric iron binding; ferrous iron binding; ferroxidase activity; iron chaperone activity; iron-sulfur cluster binding; metal ion binding; protein binding; |
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FXN-3162H | Recombinant Human FXN Protein, Myc/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Cell & Tissue Lysates | ||
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Not For Human Consumption!
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