Recombinant Human FLCN Protein, His&SUMO-tagged

• Cat.No.: FLCN-937H
• Product Overview: Recombinant Human FLCN Protein (Arg341-Asn579) with His&SUMO tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His&SUMO
• Protein Length: Arg341-Asn579
• Description: This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 40.6 kDa; Accurate Molecular Mass: 41 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 10mM PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: FLCN folliculin [ Homo sapiens (human) ]
• Official Symbol: FLCN
• Synonyms: FLCN; folliculin; BHD; MGC17998; MGC23445; birt-Hogg-Dube syndrome protein; BHD skin lesion fibrofolliculoma protein; FLCL; FLJ45004; FLJ99377; DKFZp547A118
• Gene ID: 201163
• mRNA Refseq: NM_144606
• Protein Refseq: NP_653207
• MIM: 607273
• UniProt ID: Q8NFG4