Recombinant Human FLCN Protein, GST-tagged

• Cat.No.: FLCN-4207H
• Product Overview: Human FLCN full-length ORF ( AAH15687, 1 a.a. - 342 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene is located within the Smith-Magenis syndrome region on chromosome 17. Mutations in this gene are associated with Birt-Hogg-Dube syndrome, which is characterized by fibrofolliculomas, renal tumors, lung cysts, and pneumothorax. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq
• Molecular Mass: 63.36 kDa
• AA Sequence: MNAIVALCHFCELHGPRTLFCTEVLHAPLPQGDGNEDSPGQGEQAEEEEGGIQMNSRMRAHSPAEGASVESSSPGPKKSDMCEGCRSLAAGHPGYISHDKETSIKYVSHQHPSHPQLFSIVRQACVRSLSCEVCPGREGPIFFGDEQHGFVFSHTFFIKDSLARGFQRWYSIITIMMDRIYLINSWPFLLGKVRGIIDELQGKALKVFEAEQFGCPQRAQRMNTAFTPFLHQRNGNAARSLTSLTSDDNLWACLHTSFAWLLKACGSRLTEKLLEGAPTEDTLVQMEKLAGEAGVLLPGPWPGWPWGGTSCLLSWQESLREGNAALNQPRTSLREAHPPISV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: FLCN folliculin [ Homo sapiens ]
• Official Symbol: FLCN
• Synonyms: FLCN; folliculin; BHD; MGC17998; MGC23445; birt-Hogg-Dube syndrome protein; BHD skin lesion fibrofolliculoma protein; FLCL; FLJ45004; FLJ99377; DKFZp547A118
• Gene ID: 201163
• mRNA Refseq: NM_144606
• Protein Refseq: NP_653207
• MIM: 607273
• UniProt ID: Q8NFG4